Protein Modification Reagents
Medchemexpress LLC Azido-PEG6-azide | 1243536-56-2 | 96.2% | 376.41 g/mol | C14H28N6O6 | 5 MG
Azido-PEG6-azide is a bifunctional PEG6 linker bearing azide groups at both termini, designed for click-chemistry conjugation and linker design in small-molecule and biomolecule synthesis. It is supplied for research use and provided in small, precisely measured packs for laboratory applications.
- Bifunctional PEG6 linker with azide groups at both ends.
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation.
- Suitable for PROTAC linker synthesis and small-molecule conjugation.
- High purity (~96.2%) for reproducible synthetic results.
- Molecular weight 376.41 g/mol; formula C14H28N6O6.
- Available in small research packs, including a 5 mg option.
- Colorless to light yellow liquid; store sealed, away from moisture.
eMolecules Bromoacetamido-PEG5-azide | 1415800-37-1 | MFCD22683281 | 500mg
Broadpharm | Bromoacetamido-PEG5-azide | 500mg | 200183271 | BP-21097 | 98.000 | 1415800-37-1 | MFCD22683281 | 427.296 | C14H27BrN4O6
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Medchemexpress LLC Azido-PEG6-MS | 352439-38-4 | MFCD34471264 | >95.0% | 385.43 | C13H27N3O8S | 5 MG
Azido-PEG6-MS is an azide-terminated PEG6 linker used as a click-chemistry reagent and in PROTAC linker synthesis. It provides a short, flexible, hydrophilic spacer with a terminal azide that enables copper-catalyzed or strain-promoted azide-alkyne cycloaddition for attaching small molecules or biomolecules in medicinal chemistry and bioconjugation applications.
- Contains an azide functional group for click chemistry reactions.
- Provides a PEG6 spacer for hydrophilicity and conformational flexibility.
- Suitable for PROTAC linker synthesis and bioconjugation workflows.
- Supplied in small-scale quantities appropriate for research use.
- Compatible with common conjugation conditions, including CuAAC.
Medchemexpress LLC Biotin-PEG11-SH | 1650579-23-9 | 98.0% | C34H65N3O13S2 | 10MG
BIOTIN-PEG11-SH is a thiol-reactive biotinylation reagent featuring an 11-unit polyethylene glycol spacer and a terminal thiol (-SH). Provided as a solid with typical purity of 98%, it enables efficient biotin labeling of proteins and other biomolecules via thiol chemistry while improving solubility and reducing steric hindrance.
- Enables biotin labeling via thiol-reactive chemistry.
- Reduces steric hindrance with an 11-unit PEG spacer.
- Improves aqueous solubility of labeled biomolecules.
- Suitable for protein conjugation and affinity capture workflows.
- Provided as a stable solid with high purity for consistent results.
eMolecules m-PEG4-Mal | 1263044-81-0 | 1G | Purity: 98%
Broadpharm | m-PEG4-Mal | 1G | 1263044-81-0 | MFCD12031847 | MW:351.03
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Medchemexpress LLC 2,2,3,3-tetramethyl-4,7,10,13-tetraoxa-3-silapentadecan-15-ol | 134179-40-1 | MFCD25424114 | 97.0% | 308.49 g/mol | C14H32O5Si | 1 G
TBDMS-PEG4-OH is a tert-butyldimethylsilyl-protected PEG4 alcohol used as a PEG-based linker for PROTAC synthesis. It provides a short, flexible polyethylene glycol spacer with a protected terminal hydroxyl for downstream functionalization in bifunctional molecules and conjugation chemistry.
- TBDMS-protected terminal hydroxyl for selective deprotection.
- PEG4 spacer provides flexibility and improved solubility.
- High purity (97.0%) suitable for research applications.
- Soluble in DMSO for common laboratory workflows.
- Available in small pack sizes appropriate for discovery-stage synthesis.
STA PHARMACEUTICAL US LLC Fmoc-N-amido-PEG-9-COOH | 10 g | CAS 1191064-81-9 | MDL MFCD28385470
Fmoc-N-amido-PEG-9-COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 10 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 1191064-81-9
- MDL: MFCD28385470
- InChIKey: NEESTRVILHNOJT-UHFFFAOYSA-N
- Molecular Weight: 707.814
- Molecular Formula: C36H53NO13
- Purity: ≥95%
- Container Type: 60 mL HDPE
- Pack Size: 10 g
- Net Weight: 10 g
- Gross Weight: 25 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31-decaoxa-4-azatetratriacontan-34-oic acid
- SMILES: O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)O
![eMolecules Broadpharm / N-(DBCO-N-amido-PEG4)-N-Biotin-PEG4-t-Boc-Hydrazide / 50mg / 591908425 / BP-25523 / 98.000 / / [null] / 1112.350 / C55H81N7O15S](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502475922.JPG-250.jpg)
eMolecules Broadpharm / N-(DBCO-N-amido-PEG4)-N-Biotin-PEG4-t-Boc-Hydrazide / 50mg / 591908425 / BP-25523 / 98.000 / / [null] / 1112.350 / C55H81N7O15S
Broadpharm / N-(DBCO-N-amido-PEG4)-N-Biotin-PEG4-t-Boc-Hydrazide / 50mg / 591908425 / BP-25523 / 98.000 / / [null] / 1112.350 / C55H81N7O15S
eMolecules Hydroxy-PEG5-CH2CO2tBu | 1807530-05-7 | MFCD27977509 | 1g
Broadpharm | Hydroxy-PEG5-CH2CO2tBu | 1g | 229582202 | BP-22097 | 95.000 | 1807530-05-7 | MFCD27977509 | 352.424 | C16H32O8
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Cayman Chemical XnthIn amIn congenr 25mg
A non-selective adenosine receptor antagonist (Kbs = 83, 25, and 15 nM for rat PC 12 cells, human platelets, and rat fat cells, respectively); reduces NECA-stimulated adenylate cyclase activity in human platelets (EC50s = 1 and 0.31 μM in the presence and absence of XAC, respectively); reverses R-PIA-induced inhibition of isoproterenol-stimulated adenylate cyclase activity in rat fat cell membranes (IC50s = 146 and 26 nM in the presence and absence of XAC, respectively); reverses 2-CADO-, R-PIA-, and NECA-induced reductions in heart rate and blood pressure in rats (0.1-1.0 mg/kg); induces convulsions in mice (39.8 mg/kg)
Medchemexpress LLC 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-PEG-thiol | >95.0% | 25 MG
DSPE-PEG-SH (average MW 1,000 Da) is a thiol-terminated PEGylated phospholipid combining a DSPE lipid anchor with a polyethylene glycol spacer that ends in a reactive sulfhydryl. Supplied as a solid, it is used to introduce surface-accessible thiol groups into liposomes, lipid nanoparticles, and other lipid assemblies for bioconjugation and targeted delivery applications.
- Provides a lipid anchor for stable incorporation into bilayers.
- Contains a terminal thiol (-SH) for conjugation to thiol-reactive reagents.
- Average molecular weight ~1,000 Da for the PEG spacer.
- Facilitates surface functionalization of nanoparticles and liposomes.
- Typically supplied as a powder with high purity (≥95%).
- Useful for preparing targeted delivery systems and bioconjugates.
Cayman Chemical VH 032 LInker 1 50mg
A PROTAC precursor; has been used in the synthesis of PROTACs targeting TEAD in cancer cells
Medchemexpress LLC 2-(2-azidoethoxy)ethyl 4-methylbenzenesulfonate | 182347-24-6 | MFCD27946436 | 99.8% | 285.32 g/mol | C11H15N3O4S | 500 MG
N3-PEG2-Tos is an azide-terminated PEG2 tosylate linker used as a synthetic building block for organic synthesis and bioconjugation. The tosylate is a good leaving group for nucleophilic substitution, and the azide serves as a click-chemistry handle for rapid, selective conjugation under copper-catalyzed conditions.
- Azide functional group for copper-catalyzed azide-alkyne cycloaddition.
- Tosylate leaving group enables efficient nucleophilic substitution.
- Short PEG2 spacer provides flexibility and improved solubility in common organic solvents.
- High reported purity supports consistent reaction performance.
- Available in multiple package sizes to suit different synthesis scales.
Medchemexpress LLC Bis-PEG4-TFP ester | 1446282-42-3 | 98.0% | 590.41 g/mol | C24H22F8O8 | 50 MG
Bis-PEG4-TFP ester is a PEG-based PROTAC linker with two tetrafluorophenyl (TFP) activated ester groups that enable facile conjugation to amine-containing ligands. It is provided as a high-purity research reagent intended for use in synthesis of bifunctional molecules and linker optimization.
- Contains two TFP-activated ester termini for rapid amide formation.
- Provides a PEG4 spacer to improve solubility and molecular flexibility.
- Enables efficient coupling to primary amines under mild conditions.
- High purity suitable for research and synthetic workflows.
- Available in small pack sizes convenient for laboratory use.
Medchemexpress LLC Cholesterol-PEG-maleimide | 95.1% | 2000 Da (average) | 10 MG
Cholesterol-PEG-maleimide (average MW 2000) is a cholesterol-terminated polyethylene glycol conjugate bearing a maleimide reactive group. It self-assembles in aqueous media and is used to modify liposomes or nanoparticles and to covalently attach thiol-containing ligands via maleimide-thiol chemistry.
- Maleimide functional group reacts selectively with thiol groups to form stable thioether bonds.
- Cholesterol terminus anchors into lipid bilayers for stable surface modification.
- PEG (average MW 2000) provides steric stabilization and improved circulation time.
- Amphiphilic structure facilitates liposome and nanoparticle formulation.
- Available in small research pack sizes suitable for formulation and conjugation studies.